SNRPN antibody (AA 46-95)

Catalog No. ABIN6746188

There are 3+ publications for this product available. The Rabbit Polyclonal anti-SNRPN antibody is suitable to detect SNRPN in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Monkey and Pig. It has been validated for WB.

Quick Overview for SNRPN antibody (AA 46-95) (ABIN6746188)

Target: SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Monkey, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNRPN Antibody

Binding Specificity: AA 46-95

Specificity: Human SNRPN

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Rabbit, Guinea pig (100%) Xenopus (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa46-95 of human SNRPN (P63162, NP_003088). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Rabbit, Horse, Pig, Opossum, Guinea pig (100%), Turkey, Zebra finch, Chicken, Xenopus, Salmon, Stickleback, Zebrafish (92%), Panda, Bat (85%), Drosophila (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-SNRPN antibody (ABIN6746188)

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Buschmann, Lerner, Lee, Ronai: "The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40389-95, (2001) (PubMed).

Kovalenko, Plug, Haaf, Gonda, Ashley, Ward, Radding, Golub: "Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 7, pp. 2958-63, (1996) (PubMed).

Target Details for SNRPN

Target: SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))

Alternative Name: SNRPN

Background: Name/Gene ID: SNRPN

Synonyms: SNRPN, HCERN3, RT-LI, Sm protein D, Sm-N, Sm protein N, SMN, SNURF-SNRPN, PWCR, SM-D, SNRNP-N

Gene ID: 6638

NCBI Accession: NP_003088