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E-cadherin antibody (APC)

CDH1 Reactivity: Human FACS Host: Mouse Monoclonal 67A4 APC
Catalog No. ABIN614763
  • Target See all E-cadherin (CDH1) Antibodies
    E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
    Reactivity
    • 235
    • 96
    • 83
    • 18
    • 17
    • 12
    • 9
    • 9
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 202
    • 72
    • 7
    • 3
    Mouse
    Clonality
    • 188
    • 95
    • 1
    Monoclonal
    Conjugate
    • 135
    • 36
    • 29
    • 10
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This E-cadherin antibody is conjugated to APC
    Application
    • 202
    • 88
    • 86
    • 68
    • 53
    • 50
    • 39
    • 35
    • 29
    • 27
    • 17
    • 16
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognizes CD324 / E-cadherin, an approximately 100 kDa epithelial cell adhesion molecule, whose detection is important for determination of invasive potential of epithelial neoplasms.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Immunogen
    T-47D cells
    Clone
    67A4
    Isotype
    IgG1
    Top Product
    Discover our top product CDH1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Storage
    4 °C
  • Lin, Liao, Lee, Hung, Sayion, Chen, Kang, Huang, Cherng: "Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome." in: Journal of biomedical science, Vol. 16, pp. 105, (2009) (PubMed).

    Caberg, Hubert, Begon, Herfs, Roncarati, Boniver, Delvenne: "Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes." in: Carcinogenesis, Vol. 29, Issue 7, pp. 1441-7, (2008) (PubMed).

    Furio, Guezennec, Ducarre, Guesnet, Peguet-Navarro: "Differential effects of allergens and irritants on early differentiating monocyte-derived dendritic cells." in: European journal of dermatology : EJD, Vol. 18, Issue 2, pp. 141-7, (2008) (PubMed).

  • Target
    E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
    Alternative Name
    CD324 / Cadherin-1 (CDH1 Products)
    Synonyms
    Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E-cadherin antibody, cdh1 antibody, si:dz180o5.2 antibody, uvo antibody, lcam antibody, E-Cad antibody, XBcad antibody, l-cam antibody, xcdh1 antibody, cdhc-A antibody, xb-cad antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, uvomorulin antibody, XB-cadherin antibody, arc-1 antibody, cd324 antibody, cdhe antibody, ecad antibody, AA960649 antibody, E-cad antibody, Ecad antibody, L-CAM antibody, Um antibody, cadherin 1 antibody, si:busm1-180o5.2 antibody, cadherin 1, type 1, E-cadherin (epithelial) antibody, cadherin 1, type 1 S homeolog antibody, CDH1 antibody, si:busm1-180o5.2 antibody, cdh1 antibody, Cdh1 antibody, cdh1.S antibody
    Background
    CD324 / E-cadherin is an epithelial cell surface molecule, which provides calcium-dependent homophilic interactions with E-cadherin of another cell. These intaractions take part in morphogenetic programs controlling the maintenance of the structural and functional integrity of epithelia and affect invasive potential of epithelial neoplasms. CD324 / E-cadherin is implicated in cell growth and differentiation, cell recognition, and sorting during developmental morphogenesis, as well as in aggregation-dependent cell survival. CD324 / E-cadherin-mediated cell adhesion system is highly regulated from inside the cell by a number of intracellular signaling pathways.Synonyms: CAM 120/80, CDH1, CDHE, E-cadherin, Epithelial cadherin, UVO, Uvomorulin
    Gene ID
    999, 9606
    UniProt
    P12830
    Pathways
    WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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