ADORA1 antibody (C-Term)

Catalog No. ABIN617229

Product Details anti-ADORA1 Antibody

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADORA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: THGNSAMNPI VYAFRIQKFR VTFLKIWNDH FRCQPAPPID EDLPEERPDD

Predicted Reactivity: Cow: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 82%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ADORA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADORA1

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Alternative Name: ADORA1 (ADORA1 Products)

Synonyms: adora1-A antibody, a1R antibody, ADORA1 antibody, LOC606743 antibody, LOC100222054 antibody, RDC7 antibody, A1-AR antibody, A1AR antibody, A1R antibody, AA1R antibody, AI848715 antibody, BB176431 antibody, Ri antibody, adenosine A1 receptor L homeolog antibody, adenosine A1 receptor antibody, adenosine receptor A1 antibody, adora1.L antibody, ADORA1 antibody, adora1 antibody, LOC100222054 antibody, Adora1 antibody

Background: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Alias Symbols: RDC7
Protein Interaction Partner: SNF8, ATXN1L, EPB41L2, GRM1, P2RY1, GNAI2, GNAS, GNAO1, GNAZ, DRD1, ADA,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 134

NCBI Accession: NM_000674, NP_000665

UniProt: P30542

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane