PSMD11 antibody (Regulatory Subunit)

Catalog No. ABIN618280

The Rabbit Polyclonal anti-PSMD11 antibody (ABIN618280) specifically detects PSMD11 in ELISA, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for PSMD11 antibody (Regulatory Subunit) (ABIN618280)

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD11 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PSMD11 Antibody

Binding Specificity: AA 2-422, Regulatory Subunit

Purpose: PSMD11 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human 26S proteasome non-ATPase regulatory subunit 11 protein (2-422AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMD11

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Alternative Name: PSMD11

Background:

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.

Aliases: 26S proteasome non-ATPase regulatory subunit 11 antibody, 26S proteasome regulatory subunit 9 antibody, 26S proteasome regulatory subunit p44.5 antibody, 26S proteasome regulatory subunit RPN6 antibody, 26S proteasome regulatory subunit S9 antibody, MGC3844 antibody, p44.5 antibody, protease 26S, subunit, 9 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antibody, proteasome 26S subunit, non-ATPase, 11 antibody, PSD11_HUMAN antibody, PSMD 11 antibody, PSMD11 antibody, Rpn6 antibody, S9 antibody

UniProt: O00231

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway