MMADHC antibody
Quick Overview for MMADHC antibody (ABIN632628)
Target
See all MMADHC AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Affinity purified
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Immunogen
- C2 orf25 antibody was raised using a synthetic peptide corresponding to a region with amino acids GSSGSDESHVAAAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHL
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Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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C2orf25 Blocking Peptide, (ABIN938972), is also available for use as a blocking control in assays to test for specificity of this C2orf25 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of C0 rf25 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))
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Alternative Name
- C2orf25
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Background
- Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism.
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Molecular Weight
- 33 kDa (MW of target protein)
Target
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