MMADHC antibody (AA 26-142)

Catalog No. ABIN7159657

The Rabbit Polyclonal anti-MMADHC antibody (ABIN7159657) specifically detects MMADHC in ELISA, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for MMADHC antibody (AA 26-142) (ABIN7159657)

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMADHC antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MMADHC Antibody

Binding Specificity: AA 26-142

Purpose: MMADHC Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Methylmalonic aciduria and homocystinuria type D protein, mitochondrial protein (26-142AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MMADHC

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Alternative Name: MMADHC

Background:

Background: Involved in cobalamin metabolism (PubMed:18385497, PubMed:23415655, PubMed:24722857, PubMed:26364851). Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin (PubMed:18385497, PubMed:24722857). Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin (PubMed:23415655, PubMed:24722857). Promotes oxidation of cob(II)alamin bound to MMACHC (PubMed:26364851).

Aliases: C2orf25 antibody, cblD antibody, Chromosome 2 open reading frame 25 antibody, CL25022 antibody, Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria antibody, Methylmalonic aciduria and homocystinuria type D protein antibody, methylmalonic aciduria and homocystinuria type D protein, mitochondrial antibody, mitochondrial antibody, MMAD_HUMAN antibody, Mmadhc antibody, Protein C2orf25, mitochondrial antibody

UniProt: Q9H3L0