PNKP antibody (Middle Region)

Catalog No. ABIN633051

The Rabbit Polyclonal anti-PNKP antibody (ABIN633051) specifically detects PNKP in WB. The antibody is reactive with Human samples.

Quick Overview for PNKP antibody (Middle Region) (ABIN633051)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNKP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNKP Antibody

Binding Specificity: Middle Region

Specificity: PNKP antibody was raised against the middle region of PNKP

Purification: Affinity purified

Immunogen: PNKP antibody was raised using the middle region of PNKP corresponding to a region with amino acids ALLSASPEVVVAVGFPGAGKSTFLKKHLVSAGYVHVNRDTLGSWQRCVTT

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PNKP Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this PNKP antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PNKP antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Alternative Name: PNKP

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Molecular Weight: 57 kDa (MW of target protein)

Pathways: DNA Damage Repair, Nucleotide Phosphorylation