Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) antibody

Antigen: Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1)

Synonyms: p43, SCYE1, MGC128105, MGC154081, wu:fa95a05, zgc:154081, AIMP1, EMAP2, EMAPII

Clonality: Polyclonal

Host: Goat

Application: ELISA, Blocking Antibody (Inhibition), Western Blotting (WB)

Catalog no.: ABIN636614

Additional Information

Alternative name: EMAP II

Immunogen: EMAP II antibody was raised in goat using highly pure recombinant human EMAP-II as the immunogen.

Description: EMAP-II is a tumor derived cytokine that exerts a wide range of activities on endothelial cells, monocytes and neutrophils. EMAP-II inhibits endothelial cell proliferation, vasculogenesis, neovessel formation, and can induce apoptosis. It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils. Of clinical importance, EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues. Mature EMAP-II is an 18.3 kDa protein, which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues.

Molecular Weight: 18.3 kDa (predicted detection band MW)

Application Details

Purity: Affinity Purified

Buffer: Lyophilized from PBS, pH 7.2.

Storage: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C. Avoid repeated freeze/thaw cycles.

Research Area: Cancer, DNA/RNA, Innate Immunity, Angiogenesis, Apoptosis/Necrosis