GPR37
Reactivity: Human, Rat
IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
IHC-P: 3 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target
GPR37
(G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
Alternative Name
GPR37
Background
Endothelin receptor type B is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Two splice variants have been identified both of which bind ET1 but exhibit different responses upon binding which suggests that they may be functionally distinct.