Aryl Hydrocarbon Receptor antibody

Catalog No. ABIN636854

The Rabbit Polyclonal anti-Aryl Hydrocarbon Receptor antibody is suitable to detect Aryl Hydrocarbon Receptor in samples from Human. It has been validated for IHC (p).

Quick Overview for Aryl Hydrocarbon Receptor antibody (ABIN636854)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Purification: Affinity chromatography purified

Immunogen: AHR antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 15-20 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background: The Aryl hydrocarbon receptor (AhR or AHR) is a member of the family of basic-helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. Upon ligand binding to chemicals such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the chaperones dissociate resulting in AhR translocating into the nucleus and dimerizing with ARNT (AhR nuclear translocator), leading to changes in gene transcription.

Pathways: Regulation of Cell Size