Aryl Hydrocarbon Receptor antibody (N-Term)

Catalog No. ABIN2777386

This Rabbit Polyclonal antibody specifically detects Aryl Hydrocarbon Receptor in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Dog, Cow and Guinea Pig.

Quick Overview for Aryl Hydrocarbon Receptor antibody (N-Term) (ABIN2777386)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Binding Specificity: N-Term

Purpose: AHR Antibody - N-terminal region

Sequence: MNSSSANITY ASRKRRKPVQ KTVKPIPAEG IKSNPSKRHR DRLNTELDRL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AHR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AHR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31635-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background:

Background Information: Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AHR ligands included a variety of aromatic hydrocarbons.

Gene Name: Aryl hydrocarbon receptor

Alternative Symbols: RP85, bHLHe76

Protein Name: Aryl hydrocarbon receptor

Molecular Weight: 96kDa

Gene ID: 196

NCBI Accession: NP_001612

UniProt: P35869

Pathways: Regulation of Cell Size