PDE11A antibody

Catalog No. ABIN636958

This Rabbit Polyclonal antibody specifically detects PDE11A in IHC (p). It exhibits reactivity toward Human.

Quick Overview for PDE11A antibody (ABIN636958)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDE11A Antibody

Purification: Affinity chromatography purified

Immunogen: PDE11 A antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A

Background: Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1, 2, 3, 10 and 11 degrade bothcyclic nucleotides. These enzymes are involved in many signal transduction pathways.

Pathways: cAMP Metabolic Process