TNFRSF1A antibody

Catalog No. ABIN639333

The Mouse Monoclonal anti-TNFRSF1A antibody (ABIN639333) specifically detects TNFRSF1A in ELISA, FACS and RIA. The antibody is reactive with Human samples.

Quick Overview for TNFRSF1A antibody (ABIN639333)

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF1A antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Radioimmunoassay (RIA)

Product Details anti-TNFRSF1A Antibody

Purpose: Mouse Anti-Human CD120a

Specificity: DS-MB-00283 recognizes an extracellular domain of the 55kD human TNF receptor (p55, TNF-R1, CD120a). No binding occurs to the 75kD TNF receptor (CD120b). CD120a is weakly expressed by monocytes and granulocytes. This product may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application. The antibody inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (1-3). Removal of sodium azide is recommended prior to use in functional assays. This product is routinely tested in flow cytometry on human peripheral blood monocytes. This product reacts with Rabbit, Antibody reactivity and working conditions may vary between species.

Characteristics: Adhesion Molecule/Cell Surface

Purification: Purified

Immunogen: Purified human tumour necrosis factor receptor type 1

Isotype: IgG2a

Application Details

Application Notes: ELISA, Flow Cytometry, Radioimmunoassays

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for TNFRSF1A

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Alternative Name: CD120a

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway