HPV16 E7 antibody

Catalog No. ABIN639902

The Mouse Monoclonal anti-HPV16 E7 antibody is suitable to detect HPV16 E7 in samples from Human Papillomavirus 16 (HPV-16). It has been validated for WB and ELISA.

Quick Overview for HPV16 E7 antibody (ABIN639902)

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reactivity: Human Papillomavirus 16 (HPV-16)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPV16 E7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HPV16 E7 Antibody

Purpose: Mouse Anti-HPV 16 Oncoprotein E7

Specificity: DS-MB-03401 recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. DS-MB-03401 cross-reacts with both the monomer and dimer forms of the E7 protein of HPV-18.

Characteristics: Bacterial/Fungal/Parasitic/Viral Antigens

Purification: Purified

Immunogen: Oncoprotein E7 from human papillomavirus 16.

Isotype: IgG2a

Application Details

Application Notes: ELISA, Western Blotting

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for HPV16 E7

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Target Type: Viral Protein