HCV Core Protein antibody (AA 1-120)

Catalog No. ABIN640223

The Goat not_set anti-HCV Core Protein antibody is suitable to detect HCV Core Protein in samples from Hepatitis C Virus (HCV). It has been validated for WB and ELISA.

Quick Overview for HCV Core Protein antibody (AA 1-120) (ABIN640223)

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Reactivity: Hepatitis C Virus (HCV)

Host: Goat

Conjugate: This HCV Core Protein antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HCV Core Protein Antibody

Binding Specificity: AA 1-120

Specificity: Hepatitis C Virus Core antigen (amino acids 1-120)

Characteristics: Goat Anti-Hepatitic C Virus (HCV) Core Antigen (aa 1-120)

Purification: Purified

Immunogen: Recombinant HCV Core Antigen (genotype 1a)

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 4-5 mg/ml (OD280nm, E^0.1% = 1.4)

Buffer: 0.01M PBS, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for HCV Core Protein

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Target Type: Viral Protein

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymesubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). Ube2L3 gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. It catalyzes the covalent attachment of ubiquitin to other proteins and mediates the selective degradation of short-lived and abnormal proteins as well as playing a role in the E6/E6-AP-induced ubiquitination of p53/TP53. Expression is ubiquitous, with highest expression in testis.