V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (pTry207) antibody

Antigen: V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL)

Synonyms: Crkol, AA589403, AI325100, 1110025F07Rik, CRKL, MGC63469, zgc:63469, wu:fa55g05, wu:fj60e01

Epitope: pTry207

Host: Goat

Catalog no.: ABIN645839

Additional Information

Characteristics: Goat Anti-CRKL, with HRP-conjugated secondary antibody

Alternative name: CRKL

Swiss-Prot: NP_005198

Immunogen: Synthetic peptide with sequence C-KIFDPQNPDENE, from the C Terminus of the protein sequence according to NP_005198, was used as immunogen.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Reconstitution: Supplied as 100µg of purified antibody 0.5mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Isotype: IgG  (Matching secondary antibodies)

Description: Anti-Crkl antibody is a 33kDa adaptor protein that has been shown to activate the RAS and JUN kinase signalling pathways. Also transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential, and may mediate the transduction of intracellular signals.

Specificity: The Goat anti-CRKL antibody detects protein derived from human recombinant protein and K562 lysate at various concentrations.

Application Details

Components: HRP-conjugated secondary antibody provided along with this antibody

Storage: Store at -20 ° C, if not intended for use within a month, Keep it at 4 ° C and minimize freezing and thawing when use.

Restrictions: For Research Use only