Human Immunodeficiency Virus Type 1 (HIV-1) antibody
Quick Overview for Human Immunodeficiency Virus Type 1 (HIV-1) antibody (ABIN648032)
Target
Reactivity
Host
Conjugate
Application
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Specificity
- Purified virions, disrupted. Reacts with the whole virus. It reacts with all the major viral proteins including p17, p24, gp41, p53, p64, gp120 and gp160. Does not react with T4+human lymphocytes.
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Characteristics
- Goat Anti-Human Immunodeficiency Virus 1 (HIV-1, purified virions)
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Purification
- Purified Liquid
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Immunogen
- Human isolate, confirmed
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 4-5 mg/ml (OD280nm, E^0.1% = 1.4)
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Buffer
- 0.01M PBS, pH 7.2, No stabilizing proteins have been added.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- Human Immunodeficiency Virus Type 1 (HIV-1)
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Alternative Name
- Immunodeficiency Virus 1 (HIV-1, Purified Virions)
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Target Type
- Virus
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Background
- Goat Antibody to Human Immunodeficiency VirusGlyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits.
Target
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