FCGR1A antibody

Catalog No. ABIN6253925

This Mouse Monoclonal antibody specifically detects FCGR1A in FACS, WB, ELISA, ICC and FM. It exhibits reactivity toward Human.

Quick Overview for FCGR1A antibody (ABIN6253925)

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR1A antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)

Clone: LPR-02

Product Details anti-FCGR1A Antibody

Specificity: CD64 reacts with the Fc gamma receptor 1 (FcγR1), a glycoprotein with a molecular weight of 72 kDa. The antigen is a high-affinity receptor for IgG and is able to bind human IgG1 and IgG3. The antigen is expressed on macrophages, monocytes, and interferon γ (IFN-γ) and Granulocyte Colony Stimulating Factor (G-CSF) stimulated neutrophils.

Purification: Ion exchange column

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for FCGR1A

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Alternative Name: CD64

Background: Antigen distribution: This antibody binds to a CD64 epitope distinct from the ligand-binding site and from the clone 32.2 antibody to CD64 epitope. It shows especially high affinity binding to human mononuclear phagocytes and polymorphonuclear leukocytes exposed to IFN-γ or G-CSF. Its binding is not blocked in the presence of human IgG or immune complexes. Cellular Expression: Fc gamma receptor 1 on macrophages, monocytes and neutrophils.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process