CDX2 antibody (pSer283)

Catalog No. ABIN650838

The Rabbit Polyclonal anti-CDX2 antibody (Clone RB16600) (ABIN650838) specifically detects CDX2 in IF and DB. The antibody is reactive with Human samples.

Quick Overview for CDX2 antibody (pSer283) (ABIN650838)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: Immunofluorescence (IF), Dot Blot (DB)

Clone: RB16600

Product Details anti-CDX2 Antibody

Binding Specificity: pSer283

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S283 of human CDX2.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: CDX2

Background: The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.

Molecular Weight: 33520

Gene ID: 1045

NCBI Accession: NP_001256

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance