Opsin 1 (Cone Pigments), Medium-Wave-Sensitive (OPN1MW) (N-Term) antibody

Antigen: Opsin 1 (Cone Pigments), Medium-Wave-Sensitive (OPN1MW)

Synonyms: CBD, GCP, GOP, CBBM, COD5, OPN1MW1, OPN1MW2, MGC176615, MGC177321, MGC198468, MGC198469, Gcp, OPN1LW, RCP, OPN1MW, RH2-2, grops1, grops2, wu:fk57c11, si:zc263a23.4, RH2-3, si:zc263a23.3

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651110

Additional Information

Alternative name: OPN1MW

Gene ID: 728458

UniProt: P04001

Immunogen: This OPN1MW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 30-80 from the N-terminal region of human OPN1MW.

Isotype: Ig

Description: Other names: Green cone photoreceptor pigment, Green-sensitive opsin, GOP,GCP, OPN1MW

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This OPN1MW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 30-80 from the N-terminal region of human OPN1MW.

Molecular Weight: 40584 DA

Comments:

Background: OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Flow cytometric~~1:10~50

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of OPN1MW Antibody (N-term) (ABIN651110) in HepG2 cell line lysates (35ug/lane). OPN1MW (arrow) was detected using the purified Pab.

OPN1MW Antibody (N-term) (ABIN651110) flow cytometric analysis of HepG2 K10cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Publications

Product: Holmes, Shah, Vickery et al.: "Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies." in: PLoS ONE, Vol. 4, Issue 12, pp. e7960, 2009 (PubMed).