PAPD4 antibody (N-Term)

Catalog No. ABIN651284

The Rabbit Polyclonal anti-PAPD4 antibody has been validated for WB, IF and IHC (p). It is suitable to detect PAPD4 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for PAPD4 antibody (N-Term) (ABIN651284)

Target: PAPD4 (PAP Associated Domain Containing 4 (PAPD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26128

Product Details anti-PAPD4 Antibody

Binding Specificity: AA 58-87, N-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human GLD2.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PAPD4 antibody (ABIN651284)

Guillén-Boixet, Buzon, Salvatella, Méndez: "CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets." in: eLife, Vol. 5, (2017) (PubMed).

Target Details for PAPD4

Target: PAPD4 (PAP Associated Domain Containing 4 (PAPD4))

Alternative Name: GLD2

Background: GLD2 is cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. GLD2 does not play a role in replication-dependent histone mRNA degradation.

Molecular Weight: 56028

Gene ID: 167153

NCBI Accession: NP_001107865, NP_001107866, NP_776158

UniProt: Q6PIY7