Actin-Like 6B antibody (N-Term)

Catalog No. ABIN651520

This Rabbit Polyclonal antibody specifically detects Actin-Like 6B in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Actin-Like 6B antibody (N-Term) (ABIN651520)

Target: Actin-Like 6B (ACTL6B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin-Like 6B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26766

Product Details anti-Actin-Like 6B Antibody

Binding Specificity: AA 42-70, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACTL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human ACTL6B.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Actin-Like 6B

Target: Actin-Like 6B (ACTL6B)

Alternative Name: ACTL6B

Background: ACTL6B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.

Molecular Weight: 46877

Gene ID: 51412

NCBI Accession: NP_057272

UniProt: O94805