ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 10 (ABCB10) (N-Term) antibody

Antigen: ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 10 (ABCB10)

Synonyms: M-ABC2, MTABC2, EST20237, Abc-me, Abcb12, C76534, AU016331, MGC109142, ABCB10, si:dkey-162b3.3

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN652180

Additional Information

Alternative name: ABCB10

Gene ID: 23456

UniProt: NP_036221

Immunogen: This ABCB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7~37 amino acids from the N-terminal region of human ABCB10.

Isotype: Ig

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ABCB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7~37 amino acids from the N-terminal region of human ABCB10.

Molecular Weight: 79098 DA

Comments:

Background: The membrane-associated protein ABCB10 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.

Application Details

Application Notes: The suggested dilution will be: ELISA~~1:1,000 Western blotting~~1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.10% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca

Research Area: Cell Structure

Restrictions: For Research Use only

Images

ABCB10 Antibody (S16) (ABIN652180) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ABCB10 antibody detected the ABCB10 protein (arrow).

ABCB10 antibody (N-term) (ABIN652180)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCB10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Zhang, Zhang, Liu et al.: "Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23287-94, 2000 (PubMed).