CDC14A antibody

Catalog No. ABIN652436

The Rabbit Polyclonal anti-CDC14A antibody is suitable to detect CDC14A in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for CDC14A antibody (ABIN652436)

Target: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC14A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB7269

Product Details anti-CDC14A Antibody

Purification: This antibody is purified through a protein A column, followed by dialysis against PBS.

Immunogen: This Cdc14 antibody is generated from rabbits immunized with a recombinant protein encoding aa 1~379 of human cdc14.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CDC14A

Target: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Alternative Name: Cdc14

Background: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Molecular Weight: 66574

Gene ID: 8556

NCBI Accession: NP_003663, NP_201569, NP_201570

UniProt: Q9UNH5