Denatured ATG1 antibody

Catalog No. ABIN653062

This Rabbit Polyclonal antibody specifically detects in FACS, IHC (p) and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Denatured ATG1 antibody (ABIN653062)

Target: Denatured ATG1

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Clone: RB17499

Product Details

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This denatured ATG1 antibody is generated from rabbits immunized with a denatured human ATG1 recombinant protein.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Denatured ATG1

Background: ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).

Molecular Weight: 112631

Gene ID: 8408

NCBI Accession: NP_003556

UniProt: O75385