ZRANB1 antibody (C-Term)

Catalog No. ABIN653787

The Rabbit Polyclonal anti-ZRANB1 antibody (Clone RB23203) (ABIN653787) specifically detects ZRANB1 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for ZRANB1 antibody (C-Term) (ABIN653787)

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZRANB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23203

Product Details anti-ZRANB1 Antibody

Binding Specificity: AA 665-692, C-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ZRANB1

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Alternative Name: ZRANB1

Background: ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.

Molecular Weight: 80967

Gene ID: 54764

NCBI Accession: NP_060050

UniProt: Q9UGI0