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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (Center) antibody

Antigen

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10)
Synonyms MRP7, SIMRP7, EST182763, Mrp7, mFLJ00002
Binding Site
Alternatives

Center
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN654102
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information
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Alternative name ABCC10
Gene ID 89845
UniProt Q5T3U5, NP_258261.2
Immunogen This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10.
Isotype Ig
Description Other names: Multidrug resistance-associated protein 7,ABCC10,MRP7, SIMRP7
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10.
Molecular Weight 161629 DA
Comments

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Signaling, Chromatin
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Zhou, Hopper-Borge, Shen et al.: "Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance." in: Biochemical pharmacology, Vol. 77, Issue 6, pp. 993-1001, 2009 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10)", type "Antibodies"
Hosts Rabbit (23), Goat (3), Rat (3), Mouse (1)
Reactivities Human (28), Chicken (18), Cow (Bovine) (18), Dog (Canine) (18), Horse (Equine) (18), Mouse (Murine) (18), Pig (Porcine) (18), Rat (Rattus) (18)
Applications Immunofluorescence (IF) (16), Western Blotting (WB) (12), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Internal Region (2), AA 194-272 (1)