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Antibodies
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anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (Center) antibody
Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (Center) antibody
| Antigen |
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| Synonyms |
BCATc, Eca39, Bcatc, MGC105472, fj66g02, zgc:73157, wu:fj66g02, bcat1, MGC89366, MGC148803 |
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Binding Site
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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| Catalog no. |
ABIN654106 |
| Quantity |
0.1 mg (0.25 mg/ml) |
| Price |
280.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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BCAT1
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Gene ID
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586
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UniProt
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NP_001171563.1, NP_001171562.1, NP_005495.2, NP_001171564.1, NP_001171565.1, P54687
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Immunogen
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This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-115 amino acids from the Central region of human BCAT1.
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Isotype
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Ig
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Description
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Other names: Branched-chain-amino-acid aminotransferase, cytosolic,BCAT1,BCT1, ECA39
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Characteristics
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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Specificity
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This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-115 amino acids from the Central region of human BCAT1.
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Molecular Weight
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42966 DA
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Comments
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Background: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
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Application Notes
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The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100
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Concentration
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0.25 mg/ml
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Purification
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Purified
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Buffer
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage
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Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
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Research Area
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Signaling, Protein Modifications, Metabolism, Cell Structure
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Restrictions
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For Research Use only
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Product
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Eijgelsheim, Newton-Cheh, Sotoodehnia et al.: "Genome-wide association analysis identifies multiple loci related to resting heart rate." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3885-94, 2010 (PubMed).
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Alternatives for antigen "Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1)", type "Antibodies"
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Hosts
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Rabbit (33), Mouse (2)
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Reactivities
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Human (30), Mouse (Murine) (25), Rat (Rattus) (4), Dog (Canine) (2), Freshwater Flatworm (Schmidtea mediterranea) (2), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1)
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Applications
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Western Blotting (WB) (18), Immunofluorescence (IF) (16), ELISA (10), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (3), N-Term (2), Center (1), Internal Region,AA 88-115 (1)
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Alternatives 
