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Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) (Center) antibody

Antigen

Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L)
Synonyms IBD2, SEL1L1, PRO1063, SEL1-LIKE, Sel1h, AW493766, KIAA4137, mKIAA4137, SEL1L, MGC99195
Binding Site
Alternatives

Center
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN654642
Quantity 0.1 mg  (0.25 mg/ml)  (Variants)
Price 280.50 $   Plus shipping costs $45.00
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anti-Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) (Center) antibody

Additional Information
Application Details Publications Images Alternatives Variants back to top

Alternative name SEL1L
Gene ID 6400
UniProt Q9UBV2, NP_005056.3
Immunogen This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the Central region of human SEL1L.
Isotype Ig
Description Other names: Protein sel-1 homolog 1,SEL1L,TSA305
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the Central region of human SEL1L.
Molecular Weight 88755 DA
Comments

Background: May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cell Signaling, Protein Modifications, Cell Structure
Restrictions For Research Use only

Publications
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Product Cormier, Tamura, Sunryd et al.: "EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex." in: Molecular cell, Vol. 34, Issue 5, pp. 627-33, 2009 (PubMed).

Riemer, Appenzeller-Herzog, Johansson et al.: "A luminal flavoprotein in endoplasmic reticulum-associated degradation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 35, pp. 14831-6, 2009 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L)", type "Antibodies"
Hosts Rabbit (22), Goat (4), Mouse (1)
Reactivities Human (25), Cow (Bovine) (18), Mouse (Murine) (18), Pig (Porcine) (18), Rat (Rattus) (18), Dog (Canine) (1)
Applications Immunofluorescence (IF) (15), Western Blotting (WB) (11), ELISA (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Center (3), N-Term (2), Internal Region (1)