Epithelial Mitogen Homolog (Mouse) (EPGN) (N-Term) antibody

Antigen: Epithelial Mitogen Homolog (Mouse) (EPGN)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655189

Additional Information

Alternative name: EPGN

Gene ID: 255324

UniProt: Q6UW88, NP_001013460.1

Immunogen: This EPGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-59 amino acids from the N-terminal region of human EPGN.

Isotype: Ig

Description: Other names: EPGN,Epigen,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This EPGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-59 amino acids from the N-terminal region of human EPGN.

Molecular Weight: 17091 DA

Comments:

Background: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Protein Modifications, Cell Cycle, Cell Signaling

Restrictions: For Research Use only

Images

Western blot analysis of EPGN (arrow) using rabbit polyclonal EPGN Antibody (N-term) (ABIN655189). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EPGN gene.

Publications

Product: Strachan, Murison, Prestidge et al.: "Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily." in: The Journal of biological chemistry, Vol. 276, Issue 21, pp. 18265-71, 2001 (PubMed).