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Myosin VI (MYO6) (C-Term,Arg1181) antibody

Antigen

Myosin VI (MYO6)

Synonyms 95F, 95F MHC, Dm 95F, Dm95F, Dro95F, JAG, MHC95F, MYOVI, ms(3)06746, DmelCG5695, CG5695
Binding Site
Alternatives

C-Term,Arg1181

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN655513
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name MYO6
Gene ID 4646
UniProt Q9UM54, NP_004990.3
Immunogen This MYO6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1173-1203 amino acids from the C-terminal region of human MYO6.
Isotype Ig
Description Other names: Myosin-VI,MYO6,KIAA0389
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This MYO6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1173-1203 amino acids from the C-terminal region of human MYO6.
Molecular Weight 149691 DA
Comments

Background: This gene encodes a protein involved intracellular vesicle and organelle transport, especially in the hair cell of the inner ear. Mutations in this gene have been found in patients with non-syndromic autosomal dominant and recessive hearing loss.

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cell Structure, Signaling, Protein Modifications, Cell Signaling, Chromatin, Phospho-specific antibodies
Restrictions For Research Use only

Publications

Product Cho, Chen: "Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners." in: The Journal of biological chemistry, Vol. 285, Issue 35, pp. 27159-66, 2010 (PubMed).

Alternatives

Alternatives for antigen "Myosin VI (MYO6)", type "Antibodies"
Hosts Rabbit (25)
Reactivities Human (24), Dog (Canine) (18), Mouse (Murine) (18), Pig (Porcine) (18), Rat (Rattus) (18), General (1)
Applications Immunofluorescence (IF) (18), Western Blotting (WB) (10), ELISA (6), Immunohistochemistry (IHC) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
Epitopes AA 1049-1054 (1), C-Term (1), C-Term,AA 1173-1203 (1)