Single-Stranded DNA Binding Protein 1 (SSBP1) (C-Term) antibody

Antigen: Single-Stranded DNA Binding Protein 1 (SSBP1)

Synonyms: SSBP, Ssbp, MtSSB, mtDBP, 2810480P10Rik, G630031O20Rik, SSBP1, MGC133588, MGC146277, SSB, Ssbp1, Mt-SSB, DKFZp469M1528

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655538

Additional Information

Alternative name: OBFC2B

Gene ID: 79035

UniProt: Q9BQ15, NP_076973.1

Immunogen: This OBFC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-211 amino acids from the C-terminal region of human OBFC2B.

Isotype: Ig

Description: Other names: SOSS complex subunit B1,OBFC2B,SSB1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This OBFC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-211 amino acids from the C-terminal region of human OBFC2B.

Molecular Weight: 22338 DA

Comments:

Background: Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Signaling, Protein Modifications, Chromatin, Phospho-specific antibodies, Transcription Factors

Restrictions: For Research Use only

Images

OBFC2B Antibody (C-term) (ABIN655538) western blot analysis in mouse kidney tissue lysates (35ug/lane). This demonstrates the OBFC2B antibody detected the OBFC2B protein (arrow).

Publications

Product: Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Richard, Bolderson, Cubeddu et al.: "Single-stranded DNA-binding protein hSSB1 is critical for genomic stability." in: Nature, Vol. 453, Issue 7195, pp. 677-81, 2008 (PubMed).

Li, Bolderson, Kumar et al.: "HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response." in: The Journal of biological chemistry, Vol. 284, Issue 35, pp. 23525-31, 2009 (PubMed).

Huang, Gong, Ghosal et al.: "SOSS complexes participate in the maintenance of genomic stability." in: Molecular cell, Vol. 35, Issue 3, pp. 384-93, 2009 (PubMed).