Ephrin B2 (EFNB2) (Center) antibody

Antigen: Ephrin B2 (EFNB2)

Synonyms: HTKL, EPLG5, Htk-L, LERK5, MGC126226, MGC126227, MGC126228, EFNB2, efnb2, ephrin-B2, htkl, eplg5, htk-l, lerk5, ephrinB2, Epl5, ELF-2, Eplg5, Lerk5, LERK-5, NLERK-1, efnb2a, MGC68890, efnb2b

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655599

Additional Information

Alternative name: EFNB2

Gene ID: 1948

UniProt: NP_004084.1, P52799

Immunogen: This EFNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the Central region of human EFNB2.

Isotype: Ig

Description: Other names: Ephrin-B2,EFNB2,EPLG5, HTKL, LERK5

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This EFNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the Central region of human EFNB2.

Molecular Weight: 36923 DA

Comments:

Background: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Neurology, Protein Modifications, Cell Cycle, Cell Signaling, Phospho-specific antibodies

Restrictions: For Research Use only

Publications

Product: Qin, Noberini, Huan et al.: "Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity." in: The Journal of biological chemistry, Vol. 285, Issue 1, pp. 644-54, 2009 (PubMed).