Suppressor of Cytokine Signaling 4 (SOCS4) (Center) antibody

Antigen: Suppressor of Cytokine Signaling 4 (SOCS4)

Synonyms: SOCS7, DKFZp686J1568, socs4, SOCS4, Cis4, SSI4, Cish4, STAI4, Socs4, SOCS-4, SOCS-6, STATI4, HSPC060, AI447482, MGC102463, 1500012M23Rik, 5830401B18Rik, Socs7, AI427843, AU015727, AU015859, MGC143730, MGC143731, 3110032M18Rik, A730004F22Rik, SOCS6, socs6l, zgc:64107, wu:fb77f06, MGC142549, socs7, DKFZp469I1311

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655792

Additional Information

Alternative name: SOCS4

Gene ID: 122809

UniProt: NP_955453.1, NP_543143.1, Q8WXH5

Immunogen: This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the Central region of human SOCS4.

Isotype: Ig

Description: Other names: SOCS4,Suppressor of cytokine signaling 4,SOCS7

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the Central region of human SOCS4.

Molecular Weight: 50623 DA

Comments:

Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Synonyms: SOCS7, DKFZp686J1568, socs4, SOCS4, Cis4, SSI4, Cish4, STAI4, Socs4, SOCS-4, SOCS-6, STATI4, HSPC060, AI447482, MGC102463, 1500012M23Rik, 5830401B18Rik, Socs7, AI427843, AU015727, AU015859, MGC143730, MGC143731, 3110032M18Rik, A730004F22Rik, SOCS6, socs6l, zgc:64107, wu:fb77f06, MGC142549, socs7, DKFZp469I1311

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Cell Cycle, Cell Structure

Restrictions: For Research Use only

Publications

Product: Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).