Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibody

Antigen: Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1)

Synonyms: SIP, Teap, FLJ22139, p53DINP1, TP53DINP1, TP53INP1A, TP53INP1B, DKFZp434M1317, Stinp, Trp53inp1, cb1036, MGC158431, wu:fb70a09, wu:fi13h08, zgc:158431, TP53INP1

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655833

Additional Information

Alternative name: TP53INP1

Gene ID: 94241

UniProt: Q96A56, NP_001129205.1

Immunogen: This TP53INP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-218 amino acids from the C-terminal region of human TP53INP1.

Isotype: Ig

Description: Other names: Tumor protein p53-inducible nuclear protein 1,TP53INP1,P53DINP1, SIP

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This TP53INP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-218 amino acids from the C-terminal region of human TP53INP1.

Molecular Weight: 27366 DA

Comments:

Background: TP53INP1 is in response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Apoptosis/Necrosis, Cell Structure

Restrictions: For Research Use only

Images

TP53INP1 Antibody (C-term) (ABIN655833) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TP53INP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Sawaya, Yoshimura, Shimoyama et al.: "Difference of p53AIP1 mRNA expression in gastric mucosa between patients with gastric cancer and chronic gastritis infected with Helicobacter pylori." in: Journal of clinical gastroenterology, Vol. 42, Issue 4, pp. 351-5, 2008 (PubMed).

Daniele: "Insights in gastric carcinogenesis from Helicobacter pylori infection." in: Journal of clinical gastroenterology, Vol. 42, Issue 4, pp. 336-7, 2008 (PubMed).

Yeung, Yasunaga, Bennasser et al.: "Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1." in: Cancer research, Vol. 68, Issue 21, pp. 8976-85, 2008 (PubMed).

Voight, Scott, Steinthorsdottir et al.: "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis." in: Nature genetics, Vol. 42, Issue 7, pp. 579-89, 2010 (PubMed).