F2RL2 antibody (N-Term)

Catalog No. ABIN656222

The Rabbit Polyclonal anti-F2RL2 antibody is suitable to detect F2RL2 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for F2RL2 antibody (N-Term) (ABIN656222)

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31043

Product Details anti-F2RL2 Antibody

Binding Specificity: AA 21-50, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: F2RL2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for F2RL2

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Alternative Name: F2RL2

Background: Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.

Molecular Weight: 42508

Gene ID: 2151

NCBI Accession: NP_001243495, NP_004092

UniProt: O00254

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling