F2RL2 antibody (C-Term)

Catalog No. ABIN929425

Product Details anti-F2RL2 Antibody

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: F2 RL2 antibody was raised in rabbit using the C terminal of F2 L2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

F2RL2 Blocking Peptide, catalog no. 33R-7108, is also available for use as a blocking control in assays to test for specificity of this F2RL2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for F2RL2

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Alternative Name: F2RL2 (F2RL2 Products)

Synonyms: PAR-3 antibody, PAR3 antibody, par3 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, F730031A08 antibody, f2 antibody, f2rl2 antibody, coagulation factor II thrombin receptor like 2 antibody, coagulation factor II (thrombin) receptor-like 2 antibody, coagulation factor II antibody, coagulation factor II, thrombin antibody, coagulation factor II, thrombin L homeolog antibody, coagulation factor II (thrombin) receptor-like 2 L homeolog antibody, F2RL2 antibody, f2rl2 antibody, F2 antibody, F2rl2 antibody, f2.L antibody, f2rl2.L antibody

Background: Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues. Synonyms: Polyclonal F2RL2 antibody, Anti-F2RL2 antibody, coagulation factor II, thrombin receptor-like 2 antibody, PAR3 antibody.

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling