DTNA antibody (C-Term)

Catalog No. ABIN656504

The Rabbit Polyclonal anti-DTNA antibody has been validated for WB, IF and IHC (p). It is suitable to detect DTNA in samples from Human and Mouse.

Quick Overview for DTNA antibody (C-Term) (ABIN656504)

Target: DTNA (Dystrobrevin alpha (DTNA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31275

Product Details anti-DTNA Antibody

Binding Specificity: AA 692-721, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DTNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human DTNA.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DTNA

Target: DTNA (Dystrobrevin alpha (DTNA))

Alternative Name: DTNA

Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Molecular Weight: 83901

Gene ID: 1837

NCBI Accession: NP_001121647, NP_001185867, NP_001185868, NP_001185869, NP_001185871, NP_001185873, NP_001185874, NP_001381, NP_001382, NP_001383, NP_116757, NP_116760, NP_116761, NP_116762, NP_116763

UniProt: Q9Y4J8