DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (N-Term) antibody

Antigen: DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11)

Synonyms: DJ9, EDJ, ERj3, HEDJ, hDj9, ABBP2, ERdj3, ABBP-2, UNQ537, PRO1080, cb954, MGC75796, MGC81924, Dj9, ERj3p, AL024055, 1810031F23Rik

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656552

Additional Information

Alternative name: DNAJB11

Gene ID: 51726

UniProt: Q9UBS4, NP_057390.1

Immunogen: This DNAJB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human DNAJB11.

Isotype: Ig

Description: Other names: DnaJ homolog subfamily B member 11,DNAJB11,EDJ, ERJ3, HDJ9

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This DNAJB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human DNAJB11.

Molecular Weight: 40514 DA

Comments:

Background: DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: DNAJB11 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Publications

Product: Vembar, Jin, Brodsky et al.: "The mammalian Hsp40 ERdj3 requires its Hsp70 interaction and substrate-binding properties to complement various yeast Hsp40-dependent functions." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32462-71, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Bernal-Bayard, Cardenal-Muñoz, Ramos-Morales: "The Salmonella type III secretion effector, salmonella leucine-rich repeat protein (SlrP), targets the human chaperone ERdj3." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16360-8, 2010 (PubMed).