Ubiquitin Associated Protein 2 (UBAP2) (N-Term) antibody

Antigen: Ubiquitin Associated Protein 2 (UBAP2)

Synonyms: UBAP-2, FLJ22435, FLJ43947, FLJ46567, KIAA1491, bA176F3.5, AD012W, MGC158449, zgc:158449, MGC132149

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656700

Additional Information

Alternative name: UBAP2

Gene ID: 55833

UniProt: Q5T6F2, NP_060919.2

Immunogen: This UBAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-181 amino acids from the N-terminal region of human UBAP2.

Isotype: Ig

Description: Other names: Ubiquitin-associated protein 2,UBAP2,KIAA1491

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This UBAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-181 amino acids from the N-terminal region of human UBAP2.

Molecular Weight: 117116 DA

Comments:

Background: This gene is a novel gene isolated based on its expression in the human adrenal gland. The full-length protein encoded by this gene contains a UBA-domain (ubiquitin associated domain), which is a motif found in several proteins having connections to ubiquitin and the ubiquitination pathway. In addition, the protein contains a region similar to a domain found in members of the atrophin-1 family. The function of this protein has not been determined. Additional alternate splice variants may exist, but their full length nature has not been determined.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: UBAP2 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

UBAP2 Antibody (N-term) (ABIN656700) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UBAP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Soranzo, Rivadeneira, Chinappen-Horsley et al.: "Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size." in: PLoS genetics, Vol. 5, Issue 4, pp. e1000445, 2009 (PubMed).