rho GTPase Activating Protein 22 (ARHGAP22) (C-Term) antibody

Antigen: rho GTPase Activating Protein 22 (ARHGAP22)

Synonyms: RhoGAP2, RHOGAP2, MGC47316, p68RacGAP, B230341L19Rik, si:ch211-223a10.2

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656937

Additional Information

Alternative name: ARHGAP22

Gene ID: 58504

UniProt: Q7Z5H3, NP_067049.2

Immunogen: This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-633 amino acids from the C-terminal region of human ARHGAP22.

Isotype: Ig

Description: Other names: Rho GTPase-activating protein 22,ARHGAP22,RHOGAP2

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-633 amino acids from the C-terminal region of human ARHGAP22.

Molecular Weight: 76779 DA

Comments:

Background: ARHGAPs, such as ARHGAP22, encode negative regulators of Rho GTPases (see ARHA, MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: ARHGAP22 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Cell Structure

Restrictions: For Research Use only

Images

ARHGAP22 Antibody (C-term) (ABIN656937) western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane). This demonstrates the ARHGAP22 antibody detected the ARHGAP22 protein (arrow).

Publications

Product: Katoh, Katoh: "Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico." in: International journal of molecular medicine, Vol. 14, Issue 2, pp. 333-8, 2004 (PubMed).