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Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) (N-Term) antibody

Antigen

Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1)
Synonyms B7323, DRAPC1, FP7019, FLJ90166, MGC126807, MGC126809, RP4-685L9.2, APCDD1, Pgo1, MGC81551, MGC89058, Drapc1, EIG180, AB023957, AU041258
Binding Site

N-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN657279
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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anti-Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) (N-Term) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name APCDD1
Isotype Ig
Description Other names: Protein APCDD1,APCDD1,DRAPC1
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This APCDD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the N-terminal region of human APCDD1.
Comments

Background: This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.

Application Details
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Concentration 0.25 mg/ml
Purification Purified
Research Area Cell Signaling, Protein Modifications, Cell Structure
Restrictions For Research Use only

Publications
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Product Takahashi, Fujita, Furukawa et al.: "Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis." in: Cancer research, Vol. 62, Issue 20, pp. 5651-6, 2002 (PubMed).

Shimomura, Agalliu, Vonica et al.: "APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex." in: Nature, Vol. 464, Issue 7291, pp. 1043-7, 2010 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1)", type "Antibodies"
Hosts Rabbit (19)
Reactivities Chicken (19), Human (19), Mouse (Murine) (19), Rat (Rattus) (18), Turtle (1)
Applications Immunofluorescence (IF) (15), Western Blotting (WB) (4), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)