BEAN1 antibody (N-Term)

Catalog No. ABIN657309

Cited in 1 publication. The Rabbit Polyclonal anti-BEAN1 antibody (Clone RB32748) (ABIN657309) specifically detects BEAN1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for BEAN1 antibody (N-Term) (ABIN657309)

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BEAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32748

Product Details anti-BEAN1 Antibody

Binding Specificity: AA 45-73, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-BEAN1 antibody (ABIN657309)

Shapaer, Chen, Pan, Wu, Tang, Zhao, Zeng: "Elevated BEAN1 expression correlates with poor prognosis, immune evasion, and chemotherapy resistance in rectal adenocarcinoma." in: Discover oncology, Vol. 15, Issue 1, pp. 446, (2024) (PubMed).

Target Details for BEAN1

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Alternative Name: BEAN

Background: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 28626

NCBI Accession: NP_001129578, NP_001171491, NP_001184154

UniProt: Q3B7T3