Pellino 3 antibody (N-Term)

Catalog No. ABIN657376

This Rabbit Polyclonal antibody specifically detects Pellino 3 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for Pellino 3 antibody (N-Term) (ABIN657376)

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB32852

Product Details anti-Pellino 3 Antibody

Binding Specificity: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PELI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PELI3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PELI3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for Pellino 3

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Alternative Name: PELI3

Background: Toll-like receptors (TLRs, see MIM 603030) and IL1R (IL1R1, MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).

Molecular Weight: 50755

Gene ID: 246330

NCBI Accession: NP_001091980, NP_001230064, NP_001230065, NP_659502

UniProt: Q8N2H9

Pathways: Toll-Like Receptors Cascades