Pellino 3 antibody (AA 1-280)

Catalog No. ABIN7151102

Product Details anti-Pellino 3 Antibody

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase pellino homolog 3 protein (1-280AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Pellino 3

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Alternative Name: PELI3 (PELI3 Products)

Synonyms: 6030441F14Rik antibody, A930011L17 antibody, BC028931 antibody, RGD1305989 antibody, pellino 3 antibody, pellino E3 ubiquitin protein ligase family member 3 antibody, Peli3 antibody, PELI3 antibody

Background:

Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates \\\'Lys-63\\\'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.

Aliases: E3 ubiquitin protein ligase pellino homolog 3 antibody, MGC35521 antibody, PEL 13 antibody, Peli3 antibody, PELI3_HUMAN antibody, Pellino 3 antibody, Pellino 3 alpha antibody, Pellino E3 ubiquitin protein ligase family member 3 antibody, Pellino homolog 3 (Drosophila) antibody, Pellino-3 antibody, Protein pellino homolog 3 antibody

UniProt: Q8N2H9

Pathways: Toll-Like Receptors Cascades