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Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2) (N-Term) antibody
|Synonyms||KE1.5, RAB2L, HKE1.5, Rlf, Rgt2, Rab2l, rab2l, im:7136742, Ke1.5, MGC124925, RGL2, MGC139909|
Alternatives Western Blotting (WB), ELISA
|5 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This RGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human RGL2.|
|Description||Other names: Ral guanine nucleotide dissociation stimulator-like 2,RGL2,RAB2L|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This RGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human RGL2.|
|Molecular Weight||83549 DA|
Background: Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||RGL2 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.|
|Research Area||Phospho-specific antibodies, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
|RGL2 Antibody (N-term) (ABIN657382) western blot analysis in uterine tumor cell line lysates (35ug/lane). This demonstrates the RGL2 antibody detected the RGL2 protein (arrow).|
Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).
Wu, Ma, Brown et al.: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).
Ferro, Magrini, Guazzi et al.: "G-protein binding features and regulation of the RalGDS family member, RGL2." in: The Biochemical journal, Vol. 415, Issue 1, pp. 145-54, 2008 (PubMed).
Barcellos, May, Ramsay et al.: "High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000696, 2009 (PubMed).
Vigil, Martin, Williams et al.: "Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34729-40, 2010 (PubMed).