Cas Scaffolding Protein Family Member 4 (CASS4) (C-Term) antibody

Antigen: Cas Scaffolding Protein Family Member 4 (CASS4)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657438

Additional Information

Alternative name: CASS4

Gene ID: 57091

UniProt: NP_001157588.1, Q9NQ75, NP_001157587.1, NP_001157586.1, NP_065089.2

Immunogen: This CASS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 609-639 amino acids from the C-terminal region of human CASS4.

Isotype: Ig

Description: Other names: Cas scaffolding protein family member 4,CASS4,C20orf32, HEFL

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This CASS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 609-639 amino acids from the C-terminal region of human CASS4.

Molecular Weight: 75kd Isoform 2. 87144 DA

Comments:

Background: Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: CASS4 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

CASS4 Antibody (C-term) (ABIN657438) western blot analysis in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the CASS4 antibody detected the CASS4 protein (arrow).

Publications

Product: Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Singh, Dadke, Nicolas et al.: "A novel Cas family member, HEPL, regulates FAK and cell spreading." in: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1627-36, 2008 (PubMed).