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Cas Scaffolding Protein Family Member 4 (CASS4) (C-Term) antibody
Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|UniProt||NP_001157588.1, Q9NQ75, NP_001157587.1, NP_001157586.1, NP_065089.2|
|Immunogen||This CASS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 609-639 amino acids from the C-terminal region of human CASS4.|
|Description||Other names: Cas scaffolding protein family member 4,CASS4,C20orf32, HEFL|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This CASS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 609-639 amino acids from the C-terminal region of human CASS4.|
|Molecular Weight||75kd Isoform 2. 87144 DA|
Background: Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||CASS4 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.|
|Research Area||Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications|
|Restrictions||For Research Use only|
|CASS4 Antibody (C-term) (ABIN657438) western blot analysis in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the CASS4 antibody detected the CASS4 protein (arrow).|
Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).
Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).
Singh, Dadke, Nicolas et al.: "A novel Cas family member, HEPL, regulates FAK and cell spreading." in: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1627-36, 2008 (PubMed).