REC8 Homolog (Yeast) (REC8) (Center) antibody

Antigen: REC8 Homolog (Yeast) (REC8)

Synonyms: Rec8p, MGC950, REC8L1, HR21spB, mrec, Rec8L1, AW546880

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657493

Additional Information

Alternative name: REC8

Gene ID: 9985

UniProt: NP_005123.2, NP_001041670.1, O95072

Immunogen: This REC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the Central region of human REC8.

Isotype: Ig

Description: Other names: Meiotic recombination protein REC8 homolog,REC8,REC8L1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This REC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the Central region of human REC8.

Molecular Weight: 62614 DA

Comments:

Background: This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: REC8 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Cycle, Chromatin, Signaling, Cell Structure

Restrictions: For Research Use only

Images

REC8 Antibody (Center) (ABIN657493) western blot analysis in K562 cell line lysates (35ug/lane). This demonstrates the REC8 antibody detected the REC8 protein (arrow).

Publications

Product: Aston, Krausz, Laface et al.: "Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent." in: Human reproduction (Oxford, England), Vol. 25, Issue 6, pp. 1383-97, 2010 (PubMed).