REC8 antibody (N-Term)

Catalog No. ABIN2783199

The Rabbit Polyclonal anti-REC8 antibody (ABIN2783199) specifically detects REC8 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig and Horse samples.

Quick Overview for REC8 antibody (N-Term) (ABIN2783199)

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REC8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-REC8 Antibody

Binding Specificity: N-Term

Purpose: REC8 Antibody - N-terminal region

Sequence: QLQIGVIRVY SQQCQYLVED IQHILERLHR AQLQIRIDME TELPSLLLPN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against REC8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human REC8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48037-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for REC8

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Alternative Name: REC8

Background:

Background Information: This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene Name: REC8 meiotic recombination protein

Alternative Symbols: Rec8p, REC8L1, HR21spB

Protein Name: meiotic recombination protein REC8 homolog

Molecular Weight: 62kDa

Gene ID: 9985

NCBI Accession: NP_005123

UniProt: O95072