Ubiquitin Specific Peptidase 40 (USP40) (N-Term) antibody

Antigen: Ubiquitin Specific Peptidase 40 (USP40)

Synonyms: FLJ10785, FLJ42100, C730029K03, B230215L03Rik, LRRGT00071

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657495

Additional Information

Alternative name: USP40

Gene ID: 55230

UniProt: Q9NVE5, NP_060688.1

Immunogen: This USP40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human USP40.

Isotype: Ig

Description: Other names: Ubiquitin carboxyl-terminal hydrolase 40,USP40,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This USP40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human USP40.

Molecular Weight: 57kd Isoform 4(mouse). 140130 DA

Comments:

Background: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: USP40 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Protein Modifications, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

USP40 Antibody (N-term) (ABIN657495) western blot analysis in mouse spleen tissue lysates (35ug/lane). This demonstrates the USP40 antibody detected the USP40 protein (arrow).

Publications

Product: Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).

Quesada, Díaz-Perales, Gutiérrez-Fernández et al.: "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases." in: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 54-62, 2004 (PubMed).